Friday, March 14, 2008
Lymphoma: Who is Susceptible?
Lymphoma, as with virtually every other form of cancer, can strike anybody at any time during their life however some groups are more susceptible to the disease than others. Studies around the world have shown that age, gender and geographical location affect whether you have a high or low risk of developing lymphoma however there are always exceptions to these suggestions.
Age
Lymphoma is generally regarded as a disease of the elderly and this is true to a certain extent. There are many more cases reported in the over 60s than in the under 60s however this isn’t the only age group that are thought to be at risk. People over the age of 60 often have weaker immune systems than their younger counterparts and so when mutations occur in the DNA of certain cells the body cannot eradicate these defective cells and they go on to multiply and form a cancerous growth. Strong immune systems kill mutated cells before they have the chance to multiply and differentiate which means that younger people are less susceptible to lymphoma.
Unfortunately it would seem that 25-35 year olds also show a marked increase with regards to number of diagnosed lymphoma cases however researchers are still trying to figure out why this is so.
Gender
Studies have shown that men are about three times more likely to suffer from lymphoma than women. Again research is continuing into why this is so however scientists think that female hormones may play a protective role with regards to lymphoma development or alternatively that male hormones make the gender more prone to the disease. As people age the two genders levels out and the probability of a male developing lymphoma is only slightly higher than that of a female developing the disease. This confirms that hormone levels may in fact influence whether a person is susceptible to the disease or not.
Geographical location
It would seem that people living in highly developed countries such as the UK, America, Australia, Germany etc. are at a much higher risk of being diagnosed with lymphoma than those living in places like Africa and Asia. This may have a lot to do with lifestyle and environment i.e. rich fatty foods, air pollution and other carcinogenic agents may decrease a person’s resistance to DNA mutations, however it may also be due to other factors such as natural immunity and the use of prescription drugs. Again nobody knows for sure and more research is still needed.
Even though certain age groups and people in some geographical locations are more susceptible to lymphoma than others, this doesn’t mean that you are exempt from developing the disease if you don’t fall into these categories. Children as young as two years old have been diagnosed with the disease, and so it is obvious that nobody is one hundred percent safe from lymphoma. You should make a point of checking your lymph glands regularly for any signs of swelling and in addition you should definitely consult the doctor should you feel anything wrong.
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